The regulatory aspects of the food additives industry offer a backdrop to several areas of public health concern, including consumer behaviors regarding usage, safety, and effectiveness, as well as studies that address health effects from regular use of supplements. The dietary supplement industry is regulated by the Food and Drug Administration, primarily pursuant to provisions of the DSHEE. This includes only products that fit the statutory definition of a dietary supplement as defined by the U.S. Food and Drug Administration (FDA), with the exception of cannabis hemp products (CBD), which are explained below.1 Sales of herbal teas or herbal-based cosmetics are excluded.
Dietary supplements may include generic health claims, nutrient-content claims, or structural-function claims. Certain scientific verifications are required to be submitted only to the Food and Drug Administration for health claims, that is, establishing a direct link between use of a supplement and reduced risk for illness. Health Claims Dietary supplements cannot make any claims for treatment, prevention, diagnosis, mitigation, or cure of any particular medical condition (disease claim).
Sewage Treatment and Management
Herbs and supplements do not cure diabetes or provide a stand-alone treatment, but some can be combined with traditional treatments to help alleviate symptoms and lower risk for complications. Alongside these treatments, diabetics have tried a number of herbs and supplements to improve their diabetes. Treatments involve lifestyle strategies and sometimes medications, but certain complementary therapies, like herbs and supplements, can be helpful. Numerous herbs and supplements are supposed to help manage blood sugar levels, decrease resistance to insulin, and prevent diabetic complications.
When healthy eating is not sufficient to keep your blood sugar levels in check, your doctor may determine what medications would be best for you. Heart medications influence the chemical makeup of our blood, and when you change the chemical makeup of your blood by taking a water pill, it may change the effects of those medications.
Antihistamines taken along with your blood pressure medications may make blood pressure rise, and they can also make your heart beat faster. Do not drink grapefruit juice with some blood pressure medications, as this may trigger higher levels of these medications in your body, making adverse effects more likely.
If you are taking tranquilizers, sedatives, or a prescription medication to treat high blood pressure or depression, you should talk to a doctor or pharmacist before starting to use an antihistamine. Keep records of all prescription drugs, over-the-counter medications, and herbal supplements (including herbal remedies) you take. It is important that those living with Parkinsons disease tell their healthcare providers about any herbal products, vitamins, OTC medications, and changes in diet they have made regularly. People with PD who are also taking medications for asthma, steroids, birth control, cough medicines, digoxin, immune-suppressants, HIV medications, triptans (used for treating migraines) should talk with their doctor or health care professional before taking milk thistle extract, which is standardized.
There do not seem to be any reports of significant side effects, and many people use milk thistle as a supplement. On the downside, certain OTC medications used for cold and allergy symptoms may trigger more powerful effects from the blood thinner. Licorice can also lessen the effects of blood pressure medications or diuretics (urination-producing) medications, including hydrodiuril (hydrochlorothiazide) and aldactone (spironolactone).
Preliminary data also indicate that turmeric supplementation during treatment with Capecitabine can decrease rates of hand-foot syndrome. Results from a systematic review indicate that supplementation with turmeric or curcumin can benefit patients with nonalcoholic fatty liver disease through positive effects on serum concentrations of liver enzymes. There is no benefit from curcumin supplementation for patients with Alzheimers disease.
There is only limited current evidence of certain supplements having the benefits mentioned above in humans. Although nutritional supplements have shown some promise in initial studies, it is important to keep in mind that there is not enough science data to recommend them for Parkinsons disease (PD). Most herbs and supplements have not been rigorously studied as safe and effective treatments for PD. Many of the herbs used today have not been carefully evaluated by science, and some may potentially produce severe toxic effects and significant drug-drug interactions.
Few negative effects and toxicities are negligible; cardiovascular disease is a major health risk, and no herb-remedy regimen should be initiated without a thorough review of its potential effects.
In fact, according to the American Diabetes Association, diabetics are more likely to use supplements than non-diabetics. In that context, perhaps unsurprisingly, U.S. consumers spent more on dietary herbs in 2020 for immune health and stress management than at any other time. Total direct sales of herbal supplements in 2020 were greater than in both the mass-market and natural, health, and specialty channels combined.
Although approved as a medicine in Europe, Ginkgo is unapproved in the U.S. and is marketed as a food additive, typically as 40-mg pills with extract. Oral supplements (usually 1,000 mg) can be helpful, though people with serious problems with or deficiencies in dietary vitamin B12 may need injectable. For example, a combination supplement sold as a sleep aid might contain herbs or mushrooms that are known for their tranquilizing or anxiety-reducing properties, as well as other ingredients that promote sleep. Single-herb supplements, by contrast, are generally marketed with more targeted uses, though sometimes more than one. Some concerns have been raised regarding the possible side effects of Vitamin E supplements, especially in the form of Vitamin E that is generally available (alpha-tocopherol).
Instead, this suggests that Vitamin E may be potentially harmful for individuals with Parkinsons disease (PD) and it is possible that the body uses vitamin E from food more readily than from supplements in this study, however further studies are needed. There is insufficient evidence to support using bitter melon in place of insulin or medications to treat diabetes. Eating or drinking bitter melon may be a acquired taste, but taking supplements can make it more pleasurable.